GeneSplicer: a new computational method for splice site prediction
نویسندگان
چکیده
منابع مشابه
GeneSplicer: a new computational method for splice site prediction.
GeneSplicer is a new, flexible system for detecting splice sites in the genomic DNA of various eukaryotes. The system has been tested successfully using DNA from two reference organisms: the model plant Arabidopsis thaliana and human. It was compared to six programs representing the leading splice site detectors for each of these species: NetPlantGene, NetGene2, HSPL, NNSplice, GENIO and Splice...
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We present a novel classification method for splice sites prediction using support vector machine (SVM). The method first represents input sequences by sequence-based features, including the information of the distribution of tri-nucleotides and the conserved features surrounding the splice sites characterized by Markov model. An F-score based feature selection method is then used to select inf...
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Splice sites are locations in DNA which separate protein-coding regions (exons) from noncoding regions (introns). Accurate splice site detectors thus form important components of computational gene finders. We pose splice site recognition as a classification problem with the classifier learnt from a labeled data set consisting of only local information around the potential splice site. Note tha...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2001
ISSN: 1362-4962
DOI: 10.1093/nar/29.5.1185